Rebuilding Place in the Urban Space

"A community’s physical form, rather than its land uses, is its most intrinsic and enduring characteristic." [Katz, EPA] This blog focuses on place and placemaking and all that makes it work--historic preservation, urban design, transportation, asset-based community development, arts & cultural development, commercial district revitalization, tourism & destination development, and quality of life advocacy--along with doses of civic engagement and good governance watchdogging.

Monday, June 07, 2021

University of Maryland could seed a complementary biotechnology and medical education initiative in Prince George's County

I have an extensive series of pieces about how DC could have used the reconstruction of a hospital East of the River to create a complementary medical education and biotechnology research and development initiative.  (It was based on a proposal I first wrote for the Walter Reed Campus in Northwest DC, but it was too late in the process and DC had no willingness to reconsider its very dull program for the site.)

-- "Ordinary versus Extraordinary Planning around the rebuilding of the United Medical Center in Southeast Washington DC | Part One: Rearticulating the system of health and wellness care East of the River," 2018
-- "Part Two: Creating a graduate health and biotechnology research initiative on the St. Elizabeths campus," 2018
-- "Part three: the potential for donations around an expanded program," 2018
-- "Update on DC's plans to build a new United Medical Center," 2018

Even though DC has failed to think big about the new East of the River hospital, that doesn't mean it can't be applied elsewhere.

With covid, I wrote a follow up piece mentioning the new University of Maryland Medical System hospital in Largo, how it's unlikely they are taking advantage of the opportunities for innovation in health care delivery and that were they to do so, incorporating public health initiatives would be in order.

-- "More communities need to integrate health care and public health programming: Prince George's County, DC, etc.," 2020

(The comment sections of the articles have a number of follow up citations of interesting, relevant programs and information that I have come across since writing the original pieces.)

But while writing the earlier piece today, "The East-West Divide | DC area regional economic development: anchors and where they are placed matter + airports | But military spending matters the most,"  it occurred to me that the University of Maryland College Park/UMMS could do what I suggested with the former Walter Reed Army Hospital Campus in Northwest DC or the United Medical Center in Southeast DC, for the new hospital campus in Largo in Prince George's County, which is part of the "east side" of the region that lags economically.

It turns out that the newly constructed hospital is opening this week ("Long-awaited new hospital in Prince George’s to open this week," Washington Post).  From the article:
The University of Maryland Capital Region Medical Center, located near the Largo Town Center Metro station, originally was scheduled to open in 2017. But construction was delayed for years because of clashes about funding and the hospital’s size. The 620,000-square-foot, glass-paneled facility will replace the 75-year-old Prince George’s Hospital Center in Cheverly, which will transfer its patients this weekend.  ...

County officials are pushing for the hospital to anchor the creation of a bustling downtown Largo, where they are moving government buildings and actively recruiting businesses. They also want the hospital to compete with neighboring jurisdictions for top-flight medical talent, and to attract patients from Prince George’s who currently seek treatment outside the county. 

“What the hospital means for Prince Georgians, from a health-care perspective and from an economic development perspective, is that it begins the healing process,” said Prince George’s County Council member Derrick Leon Davis (D-District 6). “There’s a sense of pride . . . but also a sense that more is to come.”
FWIW, Largo's urban design is not downtown-focused at all, but very automobile-centric and the lots are very much hermetically developed in a way that is disconnected.  (Besides, I've already argued that Prince George's County should build its "downtown" out of New Carrollton, "Setting the stage for the Purple Line light rail line to be an overwhelming success: Part 4 | Making over New Carrollton as a transit-centric urban center and Prince George's County's "New Downtown".")

Plus, hospitals turn out to not be great anchors for commercial districts and spillover, because staff pretty much are given no time to leave the campus.  That being said, hospitals in Philadelphia have provided financial support to business improvement districts, and many hospitals (at least the ones that aren't broke) have provided mortgage assistance to staffers choosing to live in the neighborhood around the hospital.

The stakeholders are right on one dimension, Largo has lots of build out capacity.  Land is underutilized.  There is plenty of room in the area to add medical education and research facilities.  AND to change the urban design pattern.  I'd focus on that rather than "creating a downtown."

The UC San Francisco campus is focused on advanced medical education.  It was originally the "San Francisco medical campus" of Berkeley, but has been independent of Berkeley since 1964.

No reason that UMCP couldn't develop a health campus at Largo.  Probably University of Maryland Baltimore would see this as competitive but I see it as more complementary.  

And frankly, UMB could run the proposed PG County medical campus as they already have functioning medical, dentistry, pharmacy, and nursing schools.  College Park has only one health related school, in public health, but also Agriculture and Engineering.

As discussed in the original series, there is a significant projected shortage of physicians, especially primary care physicians, and with the failures in dealing with covid, ideally the country will begin to reinvest in public health.  And College Park is a step ahead, having a public health school already.

Creating a University of Maryland medical education and biotechnology research campus in Prince George's County would create a Maryland biotechnology triangle connecting Montgomery County (NIH, NIST, for profit biotechnology and pharmaceutical companies), Baltimore (JHU, University of Maryland Baltimore, biotech firms), and Prince George's County.

Photo: Robb Hill, via the Washington Post.

Note that from the "build it and they will come" approach to economic development [I should start using that as an index term], elected officials argue that by default the hospital will correct health inequities.  

... Many Democrats said that view didn't take into consideration the lack of medical infrastructure in Prince George’s, where residents disproportionately suffer from conditions such as heart disease and diabetes and there are far fewer physicians and hospital beds per capita than in neighboring jurisdictions. The county has 0.75 hospital beds per 1,000 residents, for example, compared to 1.47 in Montgomery County, 1.47 in Fairfax County and 3.42 in the District. 

Davis, who began pushing for a hospital in Largo when he was elected in 2011, said he still thinks the hospital should have more beds. He said he hopes that state officials support an expansion in coming years after seeing the toll of the coronavirus pandemic on the majority Black jurisdiction, which had the highest per capita case and death rates in the region. 

“Nationwide, covid highlighted the fact that there are significant disparities in health care for Black and Brown Americans . . . this hospital is going to be part of that recovery,” said former Prince George’s County executive Rushern L. Baker III (D), whose administration signed a memorandum of understanding with the University of Maryland Medical System in 2011 that led to the construction of the hospital.

I argue that building something isn't enough, you have to have a plan to address the inequities in innovative and novel ways.  Plan + building.  And ideally, a "transformational projects action plan" approach to boot.  

That's what the previous articles are about.  Also see:

-- "Health planning vs. hospital planning redux," 2006
-- "Piling on the hospital issue," 2006
-- "An opportunity for rethinking health and wellness care in the District of Columbia," 2006
-- "Speaking of rethinking how to offer "public services" and medical care," 2007
-- "Community Health Improvement Planning," 2019
-- "A glaring illustration of the need for comprehensive health and wellness planning in DC: Providence Hospital," 2018
-- "Rush Medical Center (Chicago) clues us into a gap in state and regional health care planning: planning for disaster and epidemic response," 2020

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In the original Walter Reed campus proposal, we proposed the development of health related graduate schools in conjunction with the Washington Adventist University in Takoma Park and the Royal College of Surgeons in Dublin, which has opened medical schools in other countries.

The Adventists have an advanced medical campus in Southern California, Loma Linda University, which has schools of medicine, dentistry, nursing, public health, allied health professions, and pharmacy.

Like how the Texas Medical Center in Houston has multiple medical and health-related schools from different institutions, like Baylor and the University of Texas Health Science Center, there's no reason to limit it to just one.

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Monday, April 30, 2018

Ordinary versus Extraordinary Planning around the rebuilding of the United Medical Center in Southeast Washington DC | Part Two: Creating a graduate health education and biotechnology research initiative on the St. Elizabeths campus

Combined with creating an expanded community health and economic development program as outlined in the previous entry:

-- "Ordinary versus Extraordinary Planning around the rebuilding of the United Medical Center in Southeast Washington DC | Part One: Rearticulating the system of health and wellness care East of the River"

and the follow up entries:

-- (this one) Part Two: Creating a graduate health and biotechnology research initiative on the St. Elizabeths campus
-- Part three: the potential for donations around an expanded program

the construction of a new United Medical Center hospital should be paired with the creation of a biotechnology, health, and science education and research development program on the adjacent St. Elizabeths East Campus

The city has been trying to develop that campus for the past decade, mostly unsuccessfully.

Speculative proposal for a biotechnology, science and medical education and research program at Walter Reed.  A few years ago I fell in with some people who tried to get the city to reconsider its pretty simplistic approach to the redevelopment program for the old Walter Reed medical campus in Northwest DC.

Walter Reed Hospital, Washington, D. C.Instead of tearing down the hospital--at 2.1 million square feet it epitomizes Jane Jacobs' recommendation that city's retain a large stock of old buildings to seed innovation--we called for keeping it and using it as the foundation of creating new medical and health education programs like new medical, pharmacy, and dental schools, among others, and biotechnology and science development programs.

The aim was leverage proximity to the biotechnology sector in Montgomery County, including the National Institutes of Health, hundreds of private sector businesses, the FDA, United Therapeutics which is based in Silver Spring, and health and biotechnology education programs at DC's various universities.

In doing the research for the proposal, I was surprised to find a report out of the University of Baltimore which stated that 40% of the jobs in biotech were held by people with high school, associates, and bachelor degrees.  So there was a great opportunity for workforce development as part of the proposed program.

The proposal also included a multifaceted arts center of a couple hundred thousand square feet (modeled after GoggleWorks in Reading, PA; Cablefactory in Helsinki, La Friche in Marseilles, etc.) a big maker space with analogue and digital equipment, a nonprofit organization incubator and other initiatives.

But for various reasons, this proposal did not move forward.

The city had already committed to the retail and residential program it has, and the people leading the effort for changing the approach didn't have a lot of credibility, although I wrote a killer proposal, which included a justification for how the city could justify shifting to a different path and "changing its mind."

If we had been able to obtain the Letter of Intent that we needed from a particular medical school to commit to moving the proposal forward we probably could have shifted the discussion, especially because that LOI would have meant that the local university we were working with would have gone forward on the project as a partner. Instead they moved on to other projects, including building a new science building on their campus.

The proposal died.

Still, it's a great model of a program that could be implemented for the St. E campus in combination with the creation of a new UMC, which already has a variety of allied health professions teaching at the hospital currently, in association with UDC.

Note that as one example, the University of Texas Southwestern Medical Center, today comprised of a medical school, school of biosciences, and school of allied health professions, grew out of old military barracks buildings adjacent to Parkland Hospital in Dallas. Today the center boasts Nobel Prize winners, over 3,600 faculty and 7,000+ other workers, educating more than 3,000 students, residents, and postgraduate fellows, on an annual budget of more than $1 billion.

Urban research parks and cross-university collaborations. Some universities work to strengthen the commercialization of their scientific research through the creation of allied and adjacent science parks, where units of the institution commingle with firms and nonprofit institutes. Examples include the University Park science-research park at MIT in Cambridge, Massachusetts and the biotechnology park in East Baltimore, spearheaded by Johns Hopkins University and Hospital System.

In Greensboro, North Carolina, North Carolina A&T and the local campus of the University of North Carolina have jointly developed the Joint School of Nanoscience and Nanoengineering, which anchors an affiliated science park.

Large scale urban research districts with multiple anchors. Complementing the existence of university and medical campuses, some communities have developed large scale collaborative research and practice districts with multiple anchors, such as the University Circle District in Cleveland, anchored by the Cleveland Clinic and Case Western Reserve University and the Texas Medical Center in Houston. TMC, branding itself as a “leader in collaborative medicine,” is home to 54 health-related institutions including hospitals, multiple medical and nursing schools, research institutes, and other academic programs.

Other cities are working to create their own knowledge districts by developing new collaborative efforts with the participation of multiple academic partners at the outset.

Examples include the University District in Spokane, Washington, where five universities and the community college system are developing a 50-acre higher education and medical district adjacent to the city’s Downtown on the waterfront ("Campus evolution: WSU kicks Spokane development into high gear," Spokane Spokesman-Review), and the aforementioned Cornell University and Technion Institute project in NYC

In Cambridge, Massachusetts, a similar district has developed around Kendall Square ("Alexandria Real Estate’s empire grows in Kendall Square: The area’s life sciences boom puts the developer on top," Boston Globe) involving private entities, MIT, and Harvard.

Other examples include the Phoenix Biomedical Campus and the Mars Discovery District in Toronto.

Health-centered redevelopment programs at Brooks City Base and March Air Force Base.  DC has had a hard time making much headway on redeveloping the St. Elizabeths Campus. 

As mentioned, unlike other communities aiming to redevelop old military facilities around business, technology, and science uses to stoke economic and jobs development, the Walter Reed development will focus on residential and retail with far fewer jobs than the 8,000 that were there when the campus was a medical facility. 

(Although separately Children's Hospital was able to carve out a portion of the campus, which they will use for medical research--that space would have been ideal for the development of a medical education campus.)

While researching, I learned about a couple of other initiatives that were similar to what we proposed but weren't referenced during the planning phase for WR.

At the redeveloping Brooks Air Force Base in San Antonio, the University of the Incarnate Word has created a medical school using the old base hospital as a foundation, and the new school complements the university's programs in pharmacy, optometry, nursing and allied health professions, and physical therapy.

In Riverside County, California, the redevelopment of the March Air Force Base includes the creation of the March Life Care Campus on 236 acres of the base.

When completed and anchored by a 150-bed hospital focused on mental health care, the redevelopment will include emergency care, continuing care, assisted living residences and skilled nursing facilities, research and medical office buildings, retail and restaurants, child care and fitness facilities, a performance space and a hotel. The campus will support 7,200 full-time health care related jobs.

Personalized medicine research initiative in Northern Virginia. The INOVA Hospital System, the dominant hospital group in Northern Virginia, is building a wide-ranging research, education, and clinical treatment program focused on personalized medicine based on genomic analysis and related breakthroughs, on a 117-acre campus in Fairfax County (which formerly housed Exxon-Mobil operations) with 1.2 million s.f. which they purchased for $180 million. The first new project will be the construction of the INOVA Cancer Center, which will cost $200 million for an 180,000 s.f. facility.

The initiative includes an agreement with the University of Virginia to create a new medical school as part of the program.

-- "Behind Inova's $100 million venture fund plan to invest in the region," Washington Business Journal
-- "Personalized medicine could mean big business to DC area companies," Washington Post
-- "Inova lures U-Va. to Northern Virginia with $112 research center," Washington Post

The creation of new medical schools.  While it seems like there are already too many doctors the reality is that there aren't enough primary care physicians.  As a result, new medical schools continue to be created.  Over the past few years,  new medical schools have opened in New Jersey, New York, Florida, California, Missouri, and elsewhere, including the Texas example of UIW.

An advantage of being new is the ability to introduce new curricula and methods.  For example at some of the new medical schools, students immediately go through EMT training ("Trial-by-Fire: Training New Medical School Students as EMTs," Time Magazine) as a way to bring them into contact with patients at the outset of their education and training.

Of course, existing medical schools tend to expand and their impact grows over time ("UB Medical School opens with aim to be 'catalyst for change'," Buffalo News).

Other higher education health programs.  Pharmacy, bioscience and biotechnology, allied health professions, nursing, and other programs could be developed as part of the program. This could involve relocating and/or expanding existing programs and creating new programs and facilities.


Union Square Campus, Greensboro.

In Greensboro, building from the collaboration between NC A&T and UNC, the Union Square initiative downtown is leveraging the city's many institutions of higher education and has developed a new center for local nursing workforce training and academic programs, including the launch of a new doctoral degree granting program, with the major hospital system as the primary healthcare industry partner, in a consolidated facility that opened in 2016 ("A center for nursing: Union Square Campus opens," Winston-Salem Journal).

The next phase of the Union Square Campus development is moving into cyber-security and product design ("Next phase for Union Square Campus: cybersecurity; product design," Greensboro News & Record)

Workforce development.  The University of the District of Columbia has a nursing school and already offers health professions workforce development curricula in classroom facilities at the existing United Medical Center.

Bioscience high school. The bio/technology program could also be extended to the DC Public School system through the repositioning of at least one of the high schools located East of the River as a bio/technology oriented magnet high school, through the development of joint educational programs, comparable to programs developed at the Research Triangle High School in North Carolina, the Biotechnology High School in New Jersey, and the Phoenix Union Bioscience High School, etc.

Other programs.  The Citizen Science Lab in Pittsburgh, a lab facility open to "unaffiliated" citizen scientists would be an interesting component to add ("The Promise of Community Citizen Science," Rand Institute).  The library and information sciences program for the schools and hospital could be developed in a manner also open to the general public (e.g., the San Jose State University Library is combined with the City of San Jose's Central Library).

Shared BioLab Space/Urban Bioscience initiative. In New York City various life sciences and biotechnology development initiatives include a 50,000-square-foot biotech co-working center, created by the NYU Langone Medical Center in conjunction with national shared lab-space provider BioLabs on the space. According to a press release, at the facility:
BioLabs has hosted a seminar series for the startup community, leveraging the vast knowledge of its sponsor and partner network. Topics to date have included CRISPR technology, clinical trials, IPO, licensing, biologics, and VC funding. Pharmaceutical sponsors offer regularly scheduled office hours on site with employees from various department functions to provide in-person access to BioLabs residents and other invited guests.
The City of New York's LifeSci NYC initiative will contribute $5 million to the center.  Separately, the city's Economic Development Corporation has released an RFP to create a life-sciences hub and is offering up to $100 million in land, funding, and other incentives.

Recommendations

In addition to the broader community health and community economic development program suggested for the hospital project, as outlined in the previous entry, "Ordinary versus Extraordinary Planning around the rebuilding of the United Medical Center in Southeast Washington DC | Part One: Rearticulating the system of health and wellness care East of the River," this entry calls for the development of a biotechnology and health science education, research and business development initiative, adjacent to and part of the planning process for the development of a new United Medical Center hospital on the St. Elizabeths campus in Congress Heights.

1. Create a companion biotechnology and science development initiative.  Create a coordinating organization.  (One model is the Center for Innovative Technology in Northern Virginia.  Biotechnology programs in Phoenix and Greater Kansas City are others.  Consider building a wet lab building as a way to seed the program, to serve as an incubator for developing businesses.

2. Develop a graduate health education campus adjacent to the new United Medical Center, with medical, pharmacy, and allied health professional programs.  Get a letter of intent to create a medical school with a successful existing organization, such as the Royal College of Surgeons, Dublin, which has opened medical schools outside of Ireland.  Leverage this anchor to seed the development, expansion, and relocation of other health-related academic programs on site.

Another model is the RFP issued by New York City which resulted in the creation of the science and technology program on Roosevelt Island as a collaboration of Cornell University and the Technion Institute of Israel ("High tech and high design, Cornell's Roosevelt Island campus opens," New York Times).

3. Land anchor companies.  Area firms like Sucampo Pharmaceuticals and United Therapeutics ("United Therapeutics Corp. buys two D.C. buildings," Washington Business Journal) should be brought on board as early entry anchors.  UT, based in Silver Spring, has bought some buildings located in DC, and may have some interest in locating some operations in the city.

4. Create a bioscience high school program and companion workforce development programs.

Benefits

Creating an economic development position for the St. Elizabeths campus.  The value of creating a viable economic development program for the St. Elizabeths program is significant, and will contribute both to the economic improvement of the East of the River section of the city as well as the city more generally, in terms of broadening the local economy beyond its dependence on federal government related activity.

Lowering community health and human services costs.  DC spends a few billion dollars each year on health and human services functions.  Creating and delivering a broader community health program and generating more positive health outcomes will have economic benefits to the city in terms of long term reduction in health care costs, while citizens will personally benefit from improved health outcomes. 

Increasing the likelihood of success for the United Medical Center by developing a broad range, innovative, transformational program.  Like Prince George's Hospital, United Medical Center has had negative economic ("DC CFO says United Medical Center is 'functionally bankrupt': 6 things to know," Becker Hospital Review) and health care outcome issues for a number of years. 

Sometimes this has been a function of management, but often it is a result of providing care to an impoverished population that tends to be sicker than average as a result of poverty, often without health insurance.

By adding a broader community health and biomedical research and education program to the new hospital, it becomes more likely that the hospital will be successful and a positive choice for potential patients rather than a choice of last resort.  This makes it more likely it could support the reinstitution of obstetrics programs ("Dangerous mistakes led to shutdown of United Medical Center obstetrics ward," Washington Post) and other higher volume, higher revenue services.

Positive economic impacts. 

Hospital.  For the purposes of this proposal, it is not unreasonable to extrapolate figures based on other economic impact studies and data produced for similar projects.  A hospital of the size proposed (104 in-patient beds) has on average 622 full-time employees and 263 part-time employees. 

According to the American Hospital Association:
each hospital job supports about two more jobs and every dollar spent by a hospital supports roughly $2.30 of additional business activity.
Although this would be a replacement hospital and without the creation of a broader program such as suggested in these blog entries, outside of construction, additional economic impact wouldn't be expected to occur.

Retail program.  The retail program outlined in the previous entry would also have positive economic impact.  A community pharmacy could be included as part of the retail offer, and could be part of the teaching program for the proposed pharmacy school.  Etc.

Biotechnology and science sector.  The science-education program is a different story.  For example, the study commissioned for the New York City Cornell-Technion project projects that 600 companies and 30,000 jobs will be created, with a $23 billion economic impact over 30 years, generating $1.4 billion in tax revenues over that time frame.

While it is hard to track down exact numbers for the economic impact of Montgomery County’s biotech industry beyond the economic impact of federal research facilities, there are 10,000 scientists working at over 300 firms. The NYC study looked at all jobs, while the data reported in Montgomery are only for workers with advanced degrees, understating actual employment.

Another way is to consider the economic experience of particular companies as a way to consider the possibilities that arise from the addition of new firms active in the local economy. For example, United Therapeutics in Silver Spring is a growing company, adding buildings and employees, with $1.33 billion in annual revenue and a market capitalization of more than $8 billion. They pay about $140 million in federal and state income taxes, as well as property taxes to local jurisdictions.

The founders of Sucampo Pharmaceuticals chose to locate in the DC area because of proximity to NIH, FDA, and the US Patent and Trademark Office (in Alexandria). The company, now located in Rockville, has 80 employees, 650 patents, about $120 million in annual revenue, and was recently acquired for more than $1 billion ("Sucampo Pharmacueuticals has officially sold for $1.2 billion to U.K. company," Washington Business Journal).  Although it is not clear if the firm will be absorbed into acquiring firm, in facilities outside of the DC area.

Economic impact of medical and health graduate schools.  Another datum is the economic impact of new medical schools. The economic impact of the new medical school at University of California-Riverside is projected to be $150 million per year when the program is fully operational in 2021. A study for the new medical school at Florida State University in Tallahassee states that $2.50 is generated for each dollar invested, while a similar study for the University of Central Florida in Orlando found that $13 was generated for each dollar of investment.

However, the average economic impact of a mature medical school affiliated with a university is $1.7 billion, based on an annual research program conducted for the American Association of Medical Colleges. But the economic impact for a new medical school when there are existing schools is estimated to be less, $882 million.

Other economic impact data can be calculated for the development of related programs in pharmacy, allied health professions, nursing, etc.  For example a study on the University of Tennessee College of Pharmacy found an annual economic impact of more than $50 million, with the support of over 600 jobs, and an ROI of almost $30 per state dollar invested in the school.

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Wednesday, June 04, 2014

the more things change, the more they remain the same: Could McCormick Spice Co. move back to Baltimore City?

The company was founded in Baltimore in 1889 and grew through acquisition.  They left the city for quarters in Baltimore County in 1989.  Their old main headquarters building in the city is long gone.

The Baltimore Business Journal reports ("Spice company McCormick is considering 4 states for its new HQ") that the company is considering Pennsylvania, Delaware, Northern Virginia, and Maryland as sites for a new consolidated headquarters.

The article states that easy access to an international airport is highly desired, mentioning BWI Airport outside of Baltimore.

Why not just move back to Baltimore City?

Too bad the old headquarters is no long around for a triumphant return by the company.

Also see "Silicon Valley Fans San Francisco's Flames" from the Wall Street Journal about how many Silicon Valley tech firms are building up their operations in San Francisco, to have better access to quality talent, the same issue that is motivating McCormick to consider options other than their very suburban location in Baltimore County.

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In my forthcoming summary article for the EUNIC Washington Cluster "Europe in Baltimore" project, I suggested that the next phase for culture districts is to move towards knowledge clusters, and I suggest that Baltimore City and the city's higher education institutions need to consider this.

From the article:

From creative clusters to "creative economies" and knowledge quarters/knowledge precincts.  The basic precepts for the development of cultural districts as a revitalization strategy were laid down beginning in the 1980s, starting with various projects in the UK.   Researcher-consultants such as John Montgomery, Simon Roodhouse, Charles Landry and others have written extensively about "the creative city," and culture district development, planning and management.


The "Five Star" Model of Knowledge Development-Innovation Districts.  Source:  Aalto University.

As more places took on culture-based regeneration projects, the field has continued to develop and advance and define culture more broadly and integrate additional disciplines into more wider scale "creative economy" initiatives which tend to be focused on what are called "knowledge quarter" initiatives, as opposed to arts districts.  Perhaps knowledge quarter initiatives should be considered "next generation" culture district initiatives.

The Knowledge Quarter in Liverpool, which includes higher education institutions, government research facilities, private research ventures, medical and health care institutions, and research parks is one example.

-- "Liverpool City Region's Knowledge Economy: Delivering New Opportunities for Growth

Helsinki's Arabianranta district, which is centered around the design oriented University of Art and Design (now part of Aalto University) is another as is the Alexander Innovation District in Thessaloniki.  (There are many other examples around the world, including the MaRS Discovery District in Toronto.)

The URBACT publication, Creating knowledge hotspots in the city: A handbook | Practical guidelines for developing campuses, science quarters, creative districts and other knowledge hotspots, provides guidance for considering the development of broader knowledge development focused initiatives.

and...

3.  Baltimore has an incredible array of higher education institutions and while research and technology development initiatives by certain of the institutions have high profiles and there is the Baltimore Collegetown effort focused on retaining students in the metropolitan area after they graduate, there isn't the sense of Baltimore's higher education institutions operating at the scale of an integrated "knowledge quarter."  This needs to be addressed. 

Presently, there isn't a network of all of Baltimore's higher education institutions, although there are many examples of cooperation between institutions on more bi-lateral bases.  And Johns Hopkins University's president, Robert Daniels, who previously had been Provost at the University of Pennsylvania, which has a wide-ranging revitalization program within its urban interest area ("The University and Urban Revival," Judith Rodin, former president of Penn) has stepped up JHU's interaction with the city at large.

The Baltimore Student Exchange Program, like the Five College Consortium in Western Massachusetts, lets students take courses at different colleges and universities in the city, and is an initiative that can be built upon.

Could Baltimore's higher education institutions develop a network comparable to the Committee on Institutional Cooperation linking the Big 10 universities and the University of Chicago or the Washington Research Libraries Consortium in DC?

4.  Definitely there isn't a university-involved initiative within Baltimore that operates at the scale of Liverpool's Knowledge Quarter.

Could such a district be created in Baltimore, as the next generation of "culture district" development initiatives?

The way that the Arabianranta district was regenerated in association with the relocation of the University of Arts and Design and how design and information technology initiatives developed around it is another example of university-business-community revitalization that is especially relevant to the Station North Arts and Entertainment District as a way to better leverage and heighten the integration of these educational institutions into a broader program.

Also, the City of Helsinki's information technology innovation unit, Forum Virium Helsinki, a public-private partnership but also an agency of the city government, is another example that Baltimore could consider in the development of broader knowledge innovation efforts.

That being said, the East Baltimore Development Initiative, in part focused on leveraging the opportunities present within the medical research community at the adjacent Johns Hopkins University Medical School and Hospital is an example of a nascent effort along these lines.

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